BIXEPS

Technology

BIXEPS uses Muscle Magnetic Mitohormesis, a patented technology developed by researchers from NUS (Singapore) and ETH (Zurich). It works by emitting low-frequency, low-energy electromagnetic waves that penetrate muscle tissue, activating mitochondria—the energy powerhouses of cells. This stimulation enhances energy production, muscle endurance, and recovery, all without requiring physical exertion. The device is safe and non-invasive, operating at electromagnetic levels significantly lower than conventional MRI equipment and comparable to everyday household appliances like hair dryers or shavers.

Unlike traditional muscle stimulation methods, BIXEPS does not rely on electrical impulses to trigger contractions. Instead, it optimizes muscle energy production at the cellular level, helping muscles function more efficiently over time. The process encourages mitochondria to adapt and become more resilient, much like how exercise strengthens the body. By improving muscle energetics, BIXEPS supports better mobility, faster recovery, and increased muscle strength, making it an effective solution for aging individuals, athletes, and those recovering from muscle loss due to inactivity.

How BIXEPS Works ?

Phase 1: Muscle Magnetic Mitohormesis

BIXEPS emits low-frequency, low-energy electromagnetic waves that penetrate deep into muscle tissue, triggering mitochondrial activation and initiating a natural adaptive response. This process (known as Magnetic Mitohormesis), mimics the benefits of exercise by stimulating muscle activity without requiring physical strain.

Over time, this stimulation enhances muscle energy production and efficiency, helping muscles function optimally and recover more effectively. By improving mitochondrial function and cellular energy levels, BIXEPS supports muscle strength, endurance, and resilience, making movement easier and promoting overall physical well-being.

Phase 2: Mitochondria Activation

As mitochondria are activated, they power up cells to generate the energy needed for muscle function, repair, and rebuilding. This increased energy production enhances muscle performance, endurance, and recovery.

By optimizing mitochondrial function, BIXEPS enhances the body's ability to generate and utilize energy efficiently. This improvement supports faster muscle recovery, improved endurance, and greater resistance to fatigue. Additionally, better mitochondrial health contributes to overall metabolic efficiency, helping muscles sustain activity longer and adapt more effectively to physical demands.

Phase 3: Myokine Signaling

As muscles are activated, they release myokines—specialized signaling molecules that play a crucial role in metabolism, tissue regeneration, and inflammation control. These molecules travel through the bloodstream, communicating with other organs and promoting systemic health benefits beyond just muscle function.

By encouraging better metabolic efficiency, enhanced immune response, and reduced inflammation, BIXEPS supports holistic well-being. This effect is particularly beneficial for aging individuals, those recovering from injury, and individuals with muscle loss due to conditions like cancer or prolonged inactivity.

Myokine Medicine

BIXEPS bridges this gap by using Magnetic Mitohormesis to activate muscles and stimulate myokine release—mirroring the benefits of exercise without physical strain.

Myokines (signaling molecules released by muscles) play a crucial role in regeneration, reducing inflammation, and enhancing metabolism. By promoting their release, BIXEPS supports recovery, boosts overall health, and strengthens the body—just like exercise, but effortlessly.

FAQ
Frequently Asked Questions

Exercise is known to affect our immune system. Many research scientists have studied the effects of exercise on immunity and our current understanding is that moderate levels of exercise can enhance our immunity, and reduce risk of upper respiratory-tract infections.

The recommended levels of exercise has been defined as between 30 to 60 minutes of moderate to vigorous-intensity exercise, five times a week. These moderate-intensity exercises include simple activities like running or brisk-walking.

Healthy moderate exercises increase the activity of our white blood cells that fight infections and diseases, while at the same time encouraging the muscular release of anti-inflammatory hormones like Interleukin-1 receptor antagonist and Interleukin-10. These myokines help to keep our inflammatory immune response from going overboard.

Scientific studies have shown that BIXEPS magnetic mitohormesis up-regulates these anti-inflammatory myokine levels and suggest the possibility for BIXEPS to be used to manage inflammation.

Muscle loss happens naturally as we age and becomes a bigger problem with increasingly sedentary lifestyles. Maintaining muscle mass is key to preserve muscle strength, function and independence. Exercise remains the best intervenion to prevent such muscle loss.

When we exercise, our muscles contract and myokines are released to both encourage muscle regeneration and to prevent degeneration. Myokines associated with muscle mass regulation include Myostatin, Irisin, Interleukin-15 and Decorin, which have been observed to promote muscle growth and reduce muscle wastage. Other myokines like Myonectin and Fibroblast Growth Factor 21, do not only regulate muscle mass, but also influence mitochondrial health and the energy available for performance and regeneration.

BIXEPS magnetic mitohormesis was shown in pilot clinical studies to up-regulate Folistatin and Osteopontin levels. These myokines improve muscle and bone regneration respectively. After surgery, patients receiving BIXEPS were observed to have lower levels of blood biomarkers indicating muscle and bone breakdown as well. With several months of use, BIXEPS users also had improved muscle energetics which meant more energy in muscles to perform and recover.

Of note, studies have shown an inverse relationship between muscle size and its oxidative capacity, i.e. its ability to produce energy for sustained actions. BIXEPS has been shown to prefentially improve oxidative capacity within muscle. This suggests the possibility for BIXEPS to improve functional outcomes like balance and gait, without creating obvious gains in muscle mass.

 
 
 
 

Regular exercise is a robust modulator of metabolism and a powerful protective agent against metabolic disease. Both acute events driven by each exercise bout and chronic adaptations from exercise help to regulate insulin sensitivity and reduce the risk of metabolic diseases, such as type 2 diabetes. While many of the metabolic health benefits of exercise depend on skeletal muscle adaptations, there are also exercised-induced adaptations in the liver, adipose tissue, vasculature and pancreas. Myokines and other signalling molecules are involved in inter-tissue communication to bring about these metabolic health benefits.

A major myokine involved in metabolism and obesity is Adiponectin, which functions to improve insulin-sensitivity and reduce inflammation. Studies have shown that muscle can be induced to release more Adiponectin in response to high-fat diets and inflammation, providing a “protective-mechanism” agains metabolic insults. Sustained high fat diets can cause this protective response to become dysregulated. But exercise can help prevent and even reverse this damage.

Another myokine involved in maintaining healthy brain metabolism and mitochondria health is Irisin. Exercise has been shown to increase levels of circulating Irisin and its pre-cursor Fibronectin type III domain-containing protein 5 (FNDC5). Exercise has also been shown to increase levels of PGC-1α, a co-factor, through which the effects of Irisin takes place.

BIXEPS has been shown in pre-clinical models to increase FNDC5 and PGC-1α levels in sedentary animals. This suggests the possibility for BIXEPS to enhance the benefits of Irisin in both brain and mitochondria health.

There is strong evidence showing that increased physical activity is beneficial for the prevention of at least 7 types of cancer (breast, colon, endometrial, kidney, bladder, esophageal and stomach), lowering the risks of these cancers anywhere from 10% to 24% (varied percentages for the different types of cancers).

Increasing evidence also shows that the prescription of exercise can improve cancer treatment, by acting synergistically with other interventions like surgery and chemotherapy. During recovery, exercise also improves long-term survival-related health outcomes such as anxiety, depression and fatigue and increases the quality of life of cancer survivors.

One mechanism by which exercise affects cancer outcomes would be through moderating the immune system in humans. Studies suggest that the contraction of skeletal muscle facilitate immune cell infiltration into tumours via the release of a myokine, Interleukin-6. Pre-clinical models show an upregulation of Interleukin-6 levels with BIXEPS use, which suggests that synergies with immunotherapy treatment strategies could exist.

Preliminary bench-top research has also shown that the myokine “soup” produced by muscle cells exposed to BIXEPS has a direct inhibitory effect on cancer cell growth, limiting the size and vascularisaion of breast-cancer tissue in pre-clinical models.

To date, hundreds of thousands have benefitted from BIXEPS!

They experienced strength and endurance gains, and regained motor functions. ​Click HERE to find out more user stories…